Androderm Profile

Androderm Background and History

Androderm is a brand name testosterone patch manufactured by Allergan Pharmaceuticals. It was approved by the FDA in 1995 as a treatment for testosterone deficiency in men. Androderm was one of the first transdermal testosterone delivery methods to become available. It provided a convenient way to provide a continuous measured dose of testosterone through the skin.

Androderm gradually lost popularity after testosterone gels became available in the 2000s. However, it remains an FDA approved option for testosterone replacement therapy today. Generic versions are also now available.

Delivery Mechanism

Androderm patches contain a reservoir of testosterone suspended in an alcohol-based gel. When applied to the skin, the testosterone diffuses through the dermis and enters the bloodstream circumventing the liver to avoid rapid metabolism. This provides sustained testosterone levels for 24 hours with just once daily patch application.

Dosing and Administration

Androderm patch dosages range from 2.5mg to 5mg of testosterone per 24 hours. The starting dose is often 2.5mg/day, which can be increased to 5mg/day if needed to restore normal testosterone levels. Patches are applied once every 24 hours onto areas like the back, stomach, upper arms or thighs.

Effects and Benefits

Used properly, Androderm relieves testosterone deficiency symptoms by restoring circulating testosterone levels back to a normal physiological range. This provides benefits such as improved sexual function, increased muscle mass and strength, enhanced energy and mood, and reduced fatigue.

Side Effects and Precautions

Potential side effects may include skin reactions at the application site, acne, male pattern baldness, gynecomastia, testicular atrophy, and adverse lipid profile changes. Androderm should only be used under medical supervision in men clinically diagnosed with low testosterone.

Legal Status

Androderm patches are classified as a Schedule III controlled substance in the United States. A valid prescription is required to legally obtain and use them. Distribution or possession without a prescription violates federal law. Misuse may lead to criminal penalties.

In summary, Androderm transdermal testosterone patches can effectively and conveniently treat clinically diagnosed testosterone deficiency when used properly under medical supervision. Responsible and lawful use is imperative.