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These compounds have existed since the early 2000s, but even today they are being investigated as they have been shown to have many and varied applications in the field of medicine.

Uses for physical performance

Compared to steroids or prohormones, when it comes to improving a person’s physical-athletic abilities, the best option might be SARMs.

This is because anabolic steroids have many undesirable side effects ranging from acne and hair loss to enlargement of mammary glands in men, a condition known as gynecomastia.

To avoid these problems and other hormonal imbalances, SARMs stand out as they have a much more optimal safety profile since they do not cause these effects and work in a very different way.

How do Sarms work?

SARMs or Selective Androgen Receptor Modulators are so called because they act on androgen receptors selectively: they stimulate androgen receptors in such a way that muscle and bone growth is exclusively generated, unlike anabolic steroids that act selectively systemic throughout the body.

So it can be said that SARMs, with their selective action, carry precise instructions that help increase the synthesis of proteins that promote the growth of muscle and bone tissues without disturbing the endocrine system.

Therefore, an individual using any of these selective modulators (discussed later) need not worry about prostate enlargement or testicular shrinkage.

Now, let’s talk about the main effects that SARMs could promote:

• Increase muscle mass
• Increase bone density
• Provide increased strength
• Strengthen ligaments and joints

Side Effects of SARMs

Although SARMs do not have as many side effects as other substances, these too, like any other drug, have some that must be taken into account, the most frequent of which is the temporary decrease or suppression of testosterone secretion.

This temporary decrease can cause tiredness or even a slight decrease in sexual desire, however, the natural production of testosterone is usually restored quickly after a cycle of SARMs.

Not all users of SARMs experience these side effects, as it will depend on the metabolism of each person.

And in the case of women, some SARMs can have masculinizing effects, such as LGD-4033, so it is recommended that the anabolic/androgenic ratio be higher, such as that of the compounds Ostarine (MK 2866) and Testolone ( RAD 140).

Do they have an impact on estrogen levels?

No. SARMs do not aromatize, so they do not cause estrogen levels to rise.

Do they cause liver damage?

No. SARMs, unlike oral anabolic steroids, do not affect the liver. Therefore they do not require any liver protector.

Recommended uses and doses

The first thing that has to be mentioned regarding the use of SARMs is that they must be consumed in cycles. These are usually 6-12 weeks with a 1-month break between each cycle.

Other aspects to take into account:

• They are consumed orally.
• They are taken once a day for the duration of the cycle.
• There is no specific time for its consumption, and it can be eaten in the morning or at night since they have a long half-life (between 24 and 36 hours).

• The hormones in the body return to their normal ranges in an average time of 15 days after the end of each cycle.

Learn more about the different SARMs

Security Profile Strength increase Muscle gain Disadvantages Comentarios

SARMs studied in humans and frequently used

Andarine (S4) 7/10 8/10 8/10 can cause temporary problems

Of vision Buen mix entre definición, fuerza y masa muscular

Ligandrol (LGD-4033) 8/10 8/10 9/10 -Quite suppressive

-not suitable for women – El “rey de los SARMs”. – Excelentes resultados y perfil de seguridad muy alto.

Ostarine (MK-2866) 9/10 7/10 8/10 -The least potent of the SARMs – Perfil de seguridad muy alto

– Excelente elección para los principiantes y los que quieren evitar los efectos secundarios

Testolona (RAD 140) 6/10 9/10 9/10 -Quite suppressive

-may cause anxiety in some people Parece ser más potente que LGD-4033 pero no esta tan estudiado como aquel y por eso la mayoría de los usuarios prefieren usar LGD-4033

SARMs without human studies and of little use (experimental)

Security Profile Strength increase Muscle gain Disadvantages Comentarios

LGD-3303 unknown 9.5/10 10/10 -There are no studies in humans.

-Very suppressive. Vida media corta de 6 horas aproximadamente (por lo tanto se tiene que tomar 2 o 3 veces al día)

S23 unknown 9/10 9/10 Lacks human studies parece ser más o menos de la misma potencia que LGD-4033

YK-11 unknown 10/10 10/10 -There are no studies in humans.

-Very suppressive. El más potente entre los SARMs. También actúa como inhibidor de miostatina.

Más biodisponible por vía sublingual.

There are different types of SARMs, and each one has its own advantages and disadvantages, that’s why we present the following list of all the ones that are currently available:

*The “safety profile” column is a rating that represents the current consensus about the safety of the product and the potential risks of long-term use.

Frequent questions

What is the most suitable SARM for me?

Men

If you are looking to achieve good results in a short time and at the same time reduce possible side effects, it is recommended to start with Ostarine. Now, if you want the increase in muscle mass and strength to be more noticeable, the ideal option could be Ligandrol (LGD-4033).

If you already have experience with SARMS and have taken them in the past, a cycle of Testolone (RAD 140) can help you gain more strength.

Women

Ostarine, thanks to the fact that it has practically no side effects and gives excellent results. And for those with a little more experience, Testolone (RAD 140) will make them gain more strength and muscle mass.

Are they taken on an empty stomach or with meals?

At any time of the day, fasting or with meals, since the body assimilates them in the same way.

Do you have to follow any particular diet?

The diet will be adapted according to the objectives sought by the user, for example:

An individual who consumes ostarine but wants to reduce body fat to gain definition, a medium protein and low carbohydrate intake is recommended.

On the other hand, if you want to gain muscle mass and are also consuming Ligandrol, a high-protein diet is a better option.

Can different SARMs be combined?

It is best not to do it, remember that SARMs activate the same androgen receptors, when taken together they will compete with each other and the metabolism will not assimilate all the molecules of the components.

Therefore, it is not worth the investment in more than one SARM if you are going to consume them at the same time.

Can you consume alcohol during a SARM cycle?

There is no interaction between SARMs and alcohol. But since alcohol consumption inhibits muscle growth, the recommendation is not to drink excessively, especially during cycles to better take advantage of the properties of the drug and training.

Can a SARM be combined with anabolic steroids?

It is possible to use a SARM in combination with an anabolic steroid cycle, some bodybuilders do it to improve muscle mass and strength gains.

Even, and according to user testimonials, there could be a link between Testolone (RAD 140) and the most well-known steroids.

SARMs can also be used as an intermediate cycle between each steroid cycle, for those users who are users of the latter, it could be an option to maintain muscle gains from anabolics.

However, we do not recommend doing this without medical supervision. Steroids can have serious side effects.

What can I combine SARMs with to get even better results?

If you are looking to optimize the results of SARMs, you can combine them with the following products:

Cardarine, known to be an accelerator of fat metabolism and also to improve cardiovascular performance (If you want to know more about this compound read our article about cardarine)

Ibutamoren (MK-677), a potent growth hormone secretagogue (precursor)

Is any post-cycle medication needed?

The truth is that currently it is not worth doing a drug-based post-cycle after consuming SARMs. While some people take Raloxifene, Nolvadex, or Toremifene.

So, although testosterone levels return to normal values ​​naturally in 10 to 15 days after a cycle of SARMs, it can definitely help to consume a post-cycle glass of Tongkat Ali to speed up hormonal recovery.

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