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Methenolone Enanthate 100mg 10ml – Watson Steroids USA

$83.00

FORMULA:

Each 1 ml contains:

Methenolone Enanthate 100 mg

MECHANISM OF ACTION

Anabolics are steroids derived from testosterone in which it is a question of chemically reducing the androgenic and virilizing effects and increasing the anabolic actions. According to their chemical structure and function they are divided into three groups. The second group is that of Dihydrotestosterone (DHT) and derivatives, Methenolone.

Testosterone and androgens readily cross the cell membrane and bind to specific intracellular receptors, these receptors that have been purified are proteins with a molecular weight of approximately 120 kilodaltons. Its synthesis is genetically determined on the X chromosome.

DHT binds to a receptor site near a terminal carboxyl group. The steroid receptor complex is activated and transported to the cell nucleus and binds to a DNA receptor site, increasing the activity of RNA polymerase and the formation of messenger RNAs, stimulating the synthesis of cellular proteins ultimately responsible for physiopharmacological actions.

By intramuscular vis they are pharmacologically active, Testosterone is introduced by simple diffusion in daily cells given its liposolubility, in many target tissues it is enzymatically converted to DHT by the action of an enzyme called t5-alpha-reductase, it is more active than Testosterone. Biotransformation occurs in the liver, the main metabolites are eliminated in the urine.

Maximum concentrations are reached 6-11 days after the administered injection. The absolute bioavailability of Methenolone Enanthate is 100%.

Methenolone Enanthate 100mg 10ml – Watson Steroids USA

 

As for Methenolone acetate, it is the oral form and is a derivative of DHT and has a similar mechanism to all anabolic androgenic steroids.

 
It is metabolized in the liver and the elimination half-life is detected in the urine up to 5 days after a single administration and the duration is approximately 24 hours.

INDICATIONS

It is indicated in states that require increased protein synthesis to improve the general condition of the patient or prevent damage from catabolic processes such as wasting diseases, cachexia, advanced breast carcinoma or postmenopausal Osteoporosis.

POSOLOGY

Intramuscularly the dose is 100 mg every 1-2 weeks or 200 mg every 2-3-weeks. Orally 75 -150 mg daily taken for 6-8 weeks and if used with other steroids often a slightly lower dose is required (50-100 mg per day). In women the dose is 50-75 mg per day.

CONTRAINDICATIONS

Hypersensitivity to Methenolone. Concomitant use with oral anticoagulants. It is contraindicated in patients with breast cancer (male), diagnosed or suspected prostate cancer or adenoma, severe heart, liver or kidney failure, in pre-pubertal or aggressive individuals, in pregnancy, active hypercalcemia.

ADVERSE EFFECTS

The following reactions require medical monitoring: Virilization and menstrual irregularities in women, bladder irritability, and gynecomastia. Anaphylaxis, edema, erythrocytosis, gastrointestinal irritation, hypercalcemia and polycythemia, androgenic alopecia, seborrhea and acne in men and women. Carcinoma prostatic hypertrophy and priapism, testicular atrophy, oligospermia, gynecomastia, sexual impotence, reduced libido: in women, hirsutism, and acne, deepening of the voice, clitoral hypertrophy, breast and endometrial atrophy, dysmenorrhea, cholestatic jaundice, excitability, hypercholesterolemia, hypercalcemia, edema. They are adverse reactions of rare incidence during long-term therapy or with high doses, hepatic necrosis, leukopenia, hepatic purpura. Other adverse reactions are: constipation, nausea, diarrhea, infection, redness, pain or irritation at the injection site, changes in libido, stomach pain, difficulty sleeping, headaches, anxiety, depression, generalized paraesthesia, skin rash.

INTERACTIONS

Concomitant use with oral anticoagulants requires monitoring and adjustment of the anticoagulant dose. Concomitant administration with bupropion lowers the detection threshold of systemic steroids. Oral antidiabetic or insulin requirements may be modified.

PRECAUTIONS AND WARNINGS

In the palliative treatment of breast cancer, do not continue therapy if after 3 months the disease continues again or if hypercalcemia was verified in any phase of it. Serum and urinary calcium levels should be determined frequently in women with metastatic breast carcinoma under treatment with testosterone.

It is usually preferable to start treatment with full doses and adjust later to individual characteristics. Special care should be taken in patients with heart failure, high blood pressure, kidney failure, epilepsy, migraine, diabetes, bone metastases, dysmenorrhea, dyslipidemia, coagulation disorders, porphyria. Oral methenolone acetate should be taken on an empty stomach because food may decrease absorption.

RESTRICTIONS OF USE

Professional use

OVERDOSE

Frequent doses can trigger symptoms of slow remission, as it is a long-acting drug. Immediate discontinuation of the medication is recommended.

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