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Thyroid T3 T4, steroids for sale

What is the Thyroid T3 T4

Triiodothyronine, also known as T3, is very popular in bodybuilding as a thyroid hormone that affects almost every physiological process in the body, including growth and development, as well as metabolism, body temperature, and heart rate.

It is usually used for cutting or definition, since its function is to stimulate the metabolism of carbohydrates and fats, by activating the consumption of oxygen and the degradation of proteins within the cells.

The production of T3 and its prohormone thyroxine T4 is activated by the thyrotropin TSH, which is secreted by the pituitary gland, and which is regulated by a feedback process whose operation is similar to a closed loop, that is, a high concentration of T3 and T4 in the blood plasma inhibit the production of TSH in the pituitary, and on the contrary, when the concentration decreases it increases.

T3’s effects on tissues are 4 times more potent than its prohormone T4. Of the thyroid hormones produced by the body, only 20% are T3, while 80% are T4. 85% of the T3 circulating in the blood is formed by the removal of the iodine atom that is attached to the 5 carbon atom of T4.

The concentration of T3 in the blood is about one fortieth that of T4. This is due to its short average life of just 2.5 days, compared to T4, which exceeds 6 days.

Thyroid hormones in the gym

Bodybuilders take advantage of these hormones under the pharmaceutical trade name of Cytomel and Tiratricol. Cytomel and Tiratricol are the most used drugs, which stimulate the metabolism generating a faster conversion of carbohydrates, proteins and fats. Naturally, the bodybuilder is especially interested in increasing lipolysis, which leads to a high rate of fat burning. Bodybuilders with a large muscle mass usually use Cytomel for several weeks, as it helps to maintain a minimum fat volume, without the need for extreme dieting.

It should be clearly understood that Cytomel is not an anabolic or androgenic steroid, but rather a thyroid hormone. The drug contains synthetically manufactured triiodothyronine sodium, which closely resembles the natural thyroid hormone tricodide-thyronine, or L-T3. In general, athletes use low doses of Cytomel with the simultaneous use of steroids, since these become more efficient for reasons that are not fully known, although it is most likely as a consequence of a faster protein synthesis. It should be noted that, since Cytomel metabolizes proteins, the athlete must concentrate on a diet based on protein-rich foods.
This places Cytomel as more effective than commercially available L-T4 compounds such as L-thyroxine or Synthroid. Bodybuilders combining Cytomel and Tiratricol burn tremendous amounts of fat, but it should be noted that both products stimulate the central nervous system, so caution is highly recommended. Those bodybuilders with a maximum demand in cutting who help them with clenbuterol for more than 2 weeks, should add Ketotifen.

Thyroid Hormone Dosage for Gym Enthusiasts

The dosage of Cytomel must be very cautious, since it is a fairly strong and efficient thyroid hormone. It is important for the athlete to start with a low dose, increasing it slowly and evenly over several days. The vast majority of athletes start with a 25 mcg pill. (Or half a tablet of 50 mcg,) per day and increase this dose every 3 or 4 days with another 25 mcg additional

A dose greater than 75 mcg per day is not necessary or advisable since its side effects can be very pronounced, in addition to a loss of muscle mass. The best time for intake is on an empty stomach, and you should wait at least 30 minutes to eat (usually breakfast). Another option would be before bedtime, at least 2 hours after dinner. Nor should Cytomel be taken for more than 6 or 8 weeks (at most), even though there are elite athletes who double these days of intake.

Likewise, intake should be gradually reduced over the course of 1 or 2 weeks so that the thyroid reactivates again. To prevent a slight recovery of adiposity at the end of T-3 intake, clenbuterol or albuterol can be used for 2 to 3 weeks, followed by ephedrine and CLA for another 2 to 3 weeks.

Side effects of thyroid hormones

• Hand tremor.
• Nausea.
• Headache.
• High perspiration.
• Tachycardia.
• Insomnia.
• Distress.
• Irritability.
• Agitation.
• Menstrual disturbances.

Most relevant effects of T3 in gym enthusiasts

• T3 acts on most tissues within the body, increasing basal metabolism, oxygen use, and energy expended by the body.
• Stimulates the production of RNA polymerase I and II, thus increasing protein synthesis. It also increases the rate of protein degradation.
• Stimulates adrenergic receptors in glucose metabolism, thus increasing gluconeogenesis. It also potentiates the effects of insulin.
• Inhibits cholesterol and increases the number of LDL receptors, thus increasing lipolysis.
• Accelerates heart rate and force of contraction, thus increasing cardiac output and levels of β-adrenergic receptors in the myocardium. As a consequence, there is an increase in systolic pressure and a decrease in diastolic pressure.
• Stimulates the production of myelin, essential for neurotransmitters and the growth of axons. It is also important in linear bone growth in very young athletes.
• Increases the level of serotonin in the brain, specifically in the cerebral cortex, and inhibits 5HT-2 receptors, essential elements for the prevention of depressive disorders.

Frequently asked questions about thyroid hormones

Is it usual to include T3 and T4 in the definition periods?

Yes, it is very common as an adjunct to cutting cycles, the definition diet and intense cardio.

What is its efficiency to eliminate subcutaneous fat?

T3 and T4 often used in combination with clenbuterol and Primobolan plus a cutting diet and cutting routine are quite efficient in eliminating subcutaneous fat.


• Mullur R., Liu Y.Y., Brent G.A. Thyroid hormone regulation of metabolism. Physiological reviews 94 355-382 (2014).
• Kopp P., Solis J.C. Thyroid hormone synthesis. In: Wondisford F.E., Radovick S., eds. Clinical management of thyroid disease. Philadelphia: W.B. Saunders pp. 19-41 (2009).).
• Davies T.F., Yin X., Latif R. The genetics of the thyroid stimulating hormone receptor: history and relevance. Thyroid (2010).
• Smith B.R., Sanders J., Furmaniak J. TSH receptor antibodies. Thyroid 17 923-938 (2007).
• Stathatos N. Thyroid physiology. Medical Clinics of North America 96 165-173 (2012).
• Pearce E.N. The relationship between serum TSH and free T4 is not log linear and varies by age and sex. Journal of Clinical Endocrinology & Metabolism 25 156-157 (2013).


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