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Quinbolone anabolic steroid
Quinbolone Background and History
Quinbolone is a synthetic non-aromatizable oral anabolic-androgenic steroid (AAS) that was first developed in the 1960s. It was investigated for medical use but never fully pursued or approved for human applications. In the 1970s it started appearing on the black market used almost exclusively by bodybuilders and athletes.
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Quinbolone has a reputation for being a highly potent steroid that can rapidly build muscle mass and strength. However, it also has harsh side effects that limit its usability. As such, it remains relatively obscure compared to other more popular steroids.
Chemical Structure
The chemical structure of quinbolone consists of methyl-1-testosterone (another oral steroid) coupled with a pyrazolopyrimidine group at the A ring. This provides increased anabolic potency and makes it resilient to aromatization into estrogen. The addition of a 17α-methyl group also protects it from liver metabolism.
Dosages and Cycles
Typical dosages of quinbolone range from 10-30 mg per day. Cycles last from 6-8 weeks followed by an equal length off-cycle. It should always be stacked with testosterone because it completely suppresses natural testosterone production. Higher doses increase the risk of side effects without much added benefit.
Effects and Benefits
Quinbolone is valued for its ability to promote rapid lean muscle growth. Gains of up to 20 pounds in a single cycle are not uncommon. Strength also increases exponentially. The lack of water retention provides a hard, defined appearance to muscles. Increased aggression is commonly reported as well.
Other effects include increased protein synthesis, nitrogen retention, IGF-1 production and glycogenolysis. Recovery rate and endurance are enhanced. Virtually all of the effects are achieved through its strong binding affinity to the androgen receptor.
Side Effects and Health Risks
Unfortunately, quinbolone comes with a laundry list of undesirable side effects:
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- Highly liver toxic: can cause cholestasis, peliosis hepatis, necrosis
- Disrupts cholesterol by lowering HDL
- Cardiovascular strain
- Testosterone suppression
- Estrogen rebound post-cycle
- Acne, baldness, aggression
Extreme caution must be exercised when using this steroid. Liver protection supplements are absolutely essential. Short cycles are critical to avoid permanent damage.
Legal Status
Quinbolone is classified as a DEA Schedule III anabolic steroid in the United States, making it illegal to possess or distribute. It is not approved for medical use in humans. Other countries also have similar laws prohibiting and restricting its sale and use. Nonetheless it continues to be available through black market sources catering to bodybuilders willing to risk its dangers. Extreme caution is warranted if obtaining quinbolone.
In summary, quinbolone is one of the most powerful oral steroids ever developed, capable of astonishing effects, but also carrying significant health threats. Responsible and lawful use should be carefully considered before using this substance.
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